Can I take Lexapro with other medicines?

Lexapro has a low risk of interacting with other medicines in general. One important exception is the family of antidepressants called monoamine oxidase inhibitors (MAOIs). Lexapro and MAOIs should not be taken together or within 14 days of each other. As with other medicines in this class (SSRIs), caution is indicated when taking Lexapro with tricyclic antidepressants (TCAs).

As with other psychotropic drugs that interfere with serotonin reuptake, patients should be cautioned regarding the risk of bleeding associated with the concomitant use of Lexapro with NSAIDs, aspirin, or other drugs that affect coagulation. Before you begin taking Lexapro, make sure to tell your healthcare professional if you are taking any other medicines, including over-the-counter medicines, herbal remedies, diet supplements, etc.